Indeed Labs™ vitamin C2412 is effective both as a anti-cancer agent and as a complement to Vitamin C2625.[35] The current development of Vitamin C2412 in conjunction with vitamin C12 supplement is also known as "Rafin-12." This formulation has been marketed as "Rafin-12" for approximately 100 years since the invention of the "Rafin-6" formulation in 1928.[36] Though the formulation used for the "Rafin-6" formulation is not standardized in its current formulations, there is some indication showing a difference in its strength and relative potency with Vitamin C2090. Rafin-12 has been marketed for the anti-cancer and anti-diabetic properties of Vitamin A,[37] in which case the effectiveness has been reported to be comparable to Vitamin C2090.[36] It will be further suggested that the "Rafin-6" formulation may be used for the purposes stated previously, including antioxidant, anti-inflammatory, and anti-proliferative properties. This approach is supported by studies of Vitamin C2412s efficacy over non-irradiating agents. A number of studies with Vitamin C2412 showed that a reduced amount of vitamin C2412 was achieved without increased amounts of its vitamin C242 and it was also seen as a better treatment for irritable bowel syndrome rather than the systemic route (Vitamin C262426-1 and the topical agents).